Affitech A/S Publications

This is a list of key scientific presentation and publications referring to both the field of antibodies in general and Affitech discoveries and technologies in particular.
 

2010
Laura A. Sullivan1, Juliet G. Carbon1, Christina L. Roland1, Jason E. Toombs1, Mari Nyquist-Andersen2, Anita Kavlie2, Kyle Schlunegger3, James A. Richardson4, Rolf A. Brekken1,5*
r84, a Novel Therapeutic Antibody against Mouse and Human VEGF with Potent Anti-Tumor Activity and Limited Toxicity Induction
PLoS ONE | www.plosone.org 2 August 2010 | Volume 5 | Issue 8 | e12031

M. Anthony Moody,1,2 Hua-Xin Liao,1,3 S. Munir Alam,1,3,4, Richard M. Scearce,1 M. Kelly Plonk,1 Daniel M. Kozink,1 Mark S. Drinker,1, Ruijun Zhang,1 Shi-Mao Xia,1 Laura L. Sutherland,1 Georgia D. Tomaras,1,5,6. Ian P. Giles,7 John C. Kappes,8,9,10 Christina Ochsenbauer-Jambor,8, Tara G. Edmonds,9 Melina Soares,11 Gustavo Barbero,11 Donald N. Forthal,12, Gary Landucci,12 Connie Chang,13 Steven W. King,13 Anita Kavlie,14, Thomas N. Denny,1 Kwan-Ki Hwang,1 Pojen P. Chen,15 Philip E. Thorpe,11, David C. Montefiori,5 and Barton F. Haynes1,3,6
Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines
J. Exp. Med. Vol. 207 No. 4 763-776

2008
Alsøe L, Stacy JE, Fosså A, Funderud S, Brekke OH, Gaudernack G.
Identification of prostate cancer antigens by automated high-throughput filter immunoscreening
J Immunol Methods. 2008; 330 (1-2): 12-23.

Reiersen H, Berntsen G, Stassar M, Cochlovius B.
Screening human antibody libraries against carcinoma cells by affinity purification and polymerase chain reaction.
J Immunol Methods. 2008; 330 (1-2): 44-56. Epub 2007 Nov 29.

2005
Stassar, MJJG and Cochlovius, B..
A reverse Antibody Screening Approach
Euro Biotech News. 2005; 3 (4): 36.

Løset GA, Løbersli I, Kavlie A, Stacy JE, Borgen T, Kausmally L, Hvattum E, Simonsen B, Hovda MB, Brekke OH.
Construction, evaluation and refinement of a large human antibody phage library based on the IgD and IgM variable gene repertoire.
J Immunol Methods. 2005; 299 (1-2): 47-62. Epub 2005 Mar 8.

Reiersen H, Løbersli I, Løset GA, Hvattum E, Simonsen B, Stacy JE, McGregor D, Fitzgerald K, Welschof M, Brekke OH, Marvik OJ.
Covalent antibody display--an in vitro antibody-DNA library selection system.
Nucleic Acids Res. 2005; 33 (1): e10.

2004
H. Sletta, A. Nedal, T. E. V. Aune, H. Hellebust, S. Hakvåg, R. Aune, T. E. Ellingsen, S. Valla, and T. Brautaset
Broad-Host-Range Plasmid pJB658 Can Be Used for Industrial-Level Production of a Secreted Host-Toxic Single-ChainAntibody Fragment in Escherichia coli
Applied and Environmental Microbiology, 2004; 70, 7033–7039.

Kausmally L, Waalen K, Løbersli I, Hvattum E, Berntsen G, Michaelsen TE, Brekke OH.
Neutralizing human antibodies to varicella-zoster virus (VZV) derived from a VZV patient recombinant antibody library.
J Gen Virol. 2004; 85 (Pt 12): 3493-500.

2003
Stacy JE, Kausmally L, Simonsen B, Nordgard SH, Alsøe L, Michaelsen TE, Brekke OH.
Direct isolation of recombinant human antibodies against group B Neisseria meningitidis from scFv expression libraries.
J Immunol Methods. 2003; 283 (1-2): 247-59.

Brekke OH, Løset GA.
New technologies in therapeutic antibody development.
Curr Opin Pharmacol. 2003; 3(5): 544-50.

Brekke OH, Sandlie I.
Therapeutic antibodies for human diseases at the dawn of the twenty-first century.
Nat Rev Drug Discov. 2003; 2(1): 52-62. Review. Erratum in: Nat Rev Drug Discov. 2003; 2(3): 240.

Hellebust H.
Production of antibody fragments in a bioreactor.
Methods Mol Biol. 2003; 207: 437-41.

Brekke OH, Thommesen JE.
Tailoring natural effector functions. Antibody engineering beyond humanization.
Methods Mol Biol. 2003; 207: 383-91.

Braunagel M.
Construction of semisynthetic antibody libraries.
Methods Mol Biol. 2003; 207: 123-32.

Moghaddam A, Borgen T, Stacy J, Kausmally L, Simonsen B, Marvik OJ, Brekke OH, Braunagel M.
Identification of scFv antibody fragments that specifically recognize the heroin metabolite 6-monoacetylmorphine but not morphine
J Immunol Methods. 2003; 280 (1-2): 139-55.

2002
Activating T Cells With Trojan Horses - A Novel Approach to Vaccine Technology
Ole Henrik Brekke
European BioPharmaceutical Review, Spring 2002.

2001
Reiersen H, Rees AR.
The hunchback and its neighbours: proline as an environmental modulator.
Trends Biochem Sci. 2001; 26 (11): 679-84. Review.

Moghaddam A, Løbersli I, Gebhardt K, Braunagel M, Marvik OJ.
Selection and characterisation of recombinant single-chain antibodies to the hapten Aflatoxin-B1 from naive recombinant antibody libraries.
J Immunol Methods. 2001; 254 (1-2): 169-81.

1997
Braunagel M, Little M.
Construction of a semisynthetic antibody library using trinucleotide oligos.
Nucleic Acids Res. 1997 Nov 15;25(22):4690-1.