|
The repeated use of antibodies, as prophylactic or therapeutic agents to fight cancer, autoimmune or infectious diseases, requires antibodies that are non-immunogenic in humans. The antibodies selected from Affitech's libraries are of human origin, thus they are perfect reagents for in vivo administration. Affitech has a variety of vectors for the expression of the selected antibodies as scFv or Fab in bacteria or for the regeneration of intact fully human antibodies by any isotype of choice for the expression in eukaryotic cells.
Affitech's isolated human monoclonal antibodies are tailored to meet specific requirements. These includes the manipulation of the antibody formats (single chain, Fab, full length), properties such as affinity, avidity, metabolism and effector functions as well as using human antibodies as novel delivery vehicles.
|
|
